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<br> The valence of the microorganisms will be decided by pressing calmly on the cowl slip with a pointed object like the tip of a pen. When crimson blood cells become infested with the upper valence growth forms of the first parasite, their urge to merge pulls the RBCs together. Copulation between high valence microorganisms on adjacent RBC membranes account for the rouleau formations. The presence of huge rouleau could be detrimental to patients suffering from occlusive vascular diseases because it causes impairment of blood move in the small vessels that can compromise the red blood cells’ skill to alternate carbon dioxide and oxygen gases. This could cause greater blood strain so as to [Gluco Extend blood sugar support](https://trade-britanica.trade/wiki/Gluco_Extend:_Your_Ultimate_Guide_To_Glucose_Support) the availability of blood and oxygen to the tissue. Peripheral blood smears show rouleau when factors that improve ESR (erythrocyte sedimentation [Gluco Extend price and offers](https://championsleage.review/wiki/User:KrystleHollins7)) are present. Anemia, by increasing the ratio of RBCs to plasma, increases rouleau formation and accelerates sedimentation.<br> |
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